PREZODE is an international initiative promoting prevention, early detection, and resilience to rapidly respond to emerging infectious diseases of animal origin (zoonoses). It fosters multilateral collaboration with and between countries and other initiatives, to improve ecosystems management and to strengthen surveillance, with a multi-actor dynamic, thus maximizing impacts. The PREZODE initiative is based on a One Health approach, linking human health, animal health and environmental health.PREZODE works closely with the UN organization "Quadripartite" (FAO, WHO, WOAH, UNEP) and the One Health High Level Expert Panel (OHHLEP), to facilitate the development of recommendations for decision making.crédit photo IRD- Jimu, Angela