The Achieving Sustainable Partnerships for Innovation, Research and Entrepreneurship (ASPIRE) Project is a five-year, $15 million project funded by USAID and implemented by the Massachusetts Institute of Technology (MIT), Universidad del Valle de Guatemala (UVG) and the Guatemalan Exporters Association (AGEXPORT). The goal of the project is to create a world-class, replicable model for how Latin American universities and their collaborators can respond to local and regional development needs. The project implements a collaborative approach to research, teaching, innovation, entrepreneurship and tech transfer, based on the combination of local assets and knowledge with MIT's experience in the innovation ecosystem.