The Laboratory for Knowledge Inference in Medical Image Analysis, short KIMIA Lab, established in January 2024 at Mayo Clinic, envisions to conduct research at the forefront of mass image data in medical archives using machine learning schemes with ultimate goal of extracting information that cannot only support a more speedy and accurate diagnosis and treatment of many diseases but also, and more significantly, establish new quality assurance based on mining of collective knowledge and wisdom.The acronym KIMIA happens to sound like the Greek word "χυμεία" (the art of alloying metals, or alchemy). Once upon a time, scientists assumed they can find techniques to turn any metal into gold. Perhaps the gold of the 21st century would be rather buried underneath (or among) the big image data.