Urban flair blends seamlessly with southern hospitality at Hyatt Regency Louisville. Our renowned service, welcoming staff and prime setting make us the continued favorite among Louisville Kentucky hotels, whether visiting for work or fun. Indulge in the incredible choice of activities right outside the doors of our downtown Louisville hotel, from playing at Fourth Street Live! to enticing dining and shopping in our thriving central business district. Combined with our exceptional customer service, unparalleled attention to detail, the largest guestrooms in the city, and direct connection to the convention center, you'll discover why we are the preeminent choice for hotels in Louisville Kentucky.