Abbott is engaged in pharmaceuticals and manufacturing healthcare products. It developed the first HIV blood-screening test. Its product portfolio includes Norvir, a treatment for HIV; Synthroid, a synthetic thyroid hormone; Depakote, an anticonvulsant drug; and Humira, a drug for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and more. Its medical tests and diagnostic instrument systems are manufactured for usage in hospitals, laboratories, blood banks, and physician offices to diagnose and monitor diseases such as HIV, hepatitis, cancer, heart failure and metabolic disorders, and more. Abbott also operates its product manufacturing segment known as Abbott Point-of-Care. It manufactures diagnostic products for blood analysis. It also provides cardiac assays to the emergency room.It currently has 90,000 employees and operates in over 130 countries. Abbott was established in 1888 by Chicago physician Wallace Calvin Abbott. It is based in Abbott Park, North Chicago, Illinois.